Showing posts with label medical history. Show all posts
Showing posts with label medical history. Show all posts

Thursday, 15 June 2017

A Trip to Eyam: The Plague Village by Fay Bound Alberti


For as long as I can remember I have been interested in the history of the plague. I learned about the village of Eyam in Derbyshire while studying at the University of York. And a few weeks ago, I dragged my kids off for an explore. We stayed at the YHA’s Ilam Hall, an enormous, rambling place surrounded by green countryside. Perfect for a cheap base from which to explore points of interest in Derbyshire, including a trip to Eyam.





Ilam Hall, YHA

Eyam is a beautiful village in the Peak District National Park. It is most famous for an outbreak of bubonic plague that occurred in 1665, a year before the Great Fire of London. The present village was founded by Anglo-Saxons, though lead had been mined in the area since Roman times. The village was once industrial but now most of its economy is based on its status as ‘the plague village.’

That story began when a local tailor obtained a flea-infested bundle of cloth from London. Within a week the tailor’s assistant, George Vicars was dead, and more began dying in the household soon after. By pure coincidence when we stopped at Eyam we parked next to the ‘plague house’ where the outbreak had started. This house - like the others in the village where many people died - are a kind of living monument. People living there now must be used to visitors gawking up at the windows, trying to imaging how it would have been to live alongside loved ones dying of the plague: the smells, the sounds, the sights, the fear.


The ‘plague cottage’ of Eyam where the plague first broke out. The names of the dead in this and many nearby cottages are listed on signs outside

As the plague spread rapidly through the village, precautions were taken at the advice of the Reverend William Mompesson, the village rector and his Puritan Minister, Thomas Stanley. St Lawrence church was central to the lives of villagers, just as the church was generally for people in the seventeenth century, many of whom viewed the plague as God’s punishment for wrong doing (a particularly challenging thought so soon after the English Civil Wars). It was there that baptisms, weddings and funerals as well as the daily homilies on obedience and devotion reminded one of one’s place in the temporal and spiritual realms. Standing in the small church today, looking up at the now-faded wall paintings that would once have been brightly painted, one has a sense of how narrow and limited the world would have seemed if one was trapped there. Mompesson started to hold his services outside the church, as people were increasingly reluctant to stand shoulder to shoulder with their neighbours.
   



St Lawrence church at Eyam, with its famous stained-glass windows depicting the quarantine of the village and the now faded wall paintings. Can you spot the skeleton?

It was Mompesson who encouraged the villagers to isolate themselves from the outside world, quarantining its population rather than allowing the disease to spread further. The sacrifice of the people is told in a stained-glass window commemorating Eyam’s story. The number who died is disputed, but we know that at least half the village died to the plague – upwards of 273 people (the number recorded in the Eyam church register). The danger lasted for fourteen months, and it was far longer before anything like normalcy was resumed.


A list of residents who died from the plague 1665-1666, held in Eyam church

Survival was random. Several who remained alive had close contact with those who died from the plague but did not contract the disease themselves. One Elizabeth Hancock was uninfected though she buried six children and her husband in eight days. The unofficial village gravedigger Marshall Howe also survived.

Critics of the village’s quarantine have recently pointed out that wealthier residents were able to circumvent the ban.  Indeed, Mompesson sent his own children away to Sheffield so that that could escape the quarantine. He wanted his wife to go with them, but she refused, deciding instead to stay with her husband and tend to the people of Eyam. Catherine died of the plague and her grave still stands in the churchyard. Mompesson himself was forever associated with the plague and not universally welcomed at his next parish. He did remarry, however and eventually became Prebendary of Southwell, Nottinghamshire.  


The grave of Catherine Mompesson

Eyam is well worth a visit. Not just for the village itself and the glorious church which is filled with seventeenth-century detail, but also for the attractions around it. Some of these are plague-related – such as the Coolstone or Boundary stone, where money soaked in vinegar (believed to kill the infection) was placed in exchange for food and medicine for the isolated villagers. 

The Boundary Stone


You can visit Eyam museum, too, which was founded in 1994 and which tells the story of Eyam before the plague, as well as the various medical attempts to protect the villagers. This includes the traditional seventeenth-century plague doctor's costume that looks like something from a modern nightmare. The mask had a curved beak, shaped like that of a bird. Straps held the beak in place and the beak held dried flowers, including roses and carnations, herbs and camphor or vinegar. These contents were to keep away bad smells, which were believed to be the cause of plague in the seventeenth century (the theory of miasma being that bad smells were bad 'air' which was the cause of disease). 


The garb of the plague doctor, complete with beaked nose stuffed with herbs and spices. 

Much to the delight of the children, the museum also has waxwork models of people at various stages of bubonic plague, covered in sores and pustules. There is also a lot of information about rats, which spills over into the souvenirs for sale in the shop. Which is how we ended up with a pair of stuffed toy rats, Doris and Dave, who accompanied us on the rest of our tour.  





Doris and Dave explore Derbyshire 




Picture credits: 
The Boundary Stone, Wikipedia. 
Ilam Hall: yha.org.uk 



Saturday, 15 April 2017

Facing the Future as Someone Else: A History of Face Transplants by Fay Bound Alberti



Faces matter. They tell the world who we are and where we come from. They reveal our individuality, our genetics, emotions and ethnicity. But faces are also 'matter,' a composite of tissues, muscles and nerves that can be changed by cosmetics, art and surgery.  Face transplants are no longer science fiction, which they were in 1997 when Face/Off hit the cinemas, starring John Travolta and Nicholas Cage and directed by John Woo. Since 2005, it has been possible to perform face transplants, in which the face of a dead donor is overlaid on the body of a recipient. That recipient will more than likely have undergone some traumatic event or accident, and multiple reconstructive surgeries before receiving a new face. What must it be like to wake up as someone else? To have to learn to speak, eat, smile and inhabit a totally different visage? What would it be like for your family? Or for the family of the donor, constantly looking for and hoping to find (or not to find) an essence of their loved one. 

I have been thinking a lot about these kinds of questions. I'm writing a history of face transplants from the 1950s to the present, focusing especially on post 2005, when the 38-year old French woman Isabelle Dinoire became the first face transplant recipient. Hers was a partial transplant; her nose, chin and lips had been lost when she was savaged by her pet dog. Isabelle was unconscious at the time, having argued with her daughter and taken an overdose of sleeping tablets. Whether or not it was a deliberate overdose has proved contentious: could she have given true, informed consent for a face transplant when she was depressed enough to commit suicide? When she couldn't possibly have known what the world had in store for her? 

As it turned out, the world was very interested. The hospital that treated her released pre- and post- operative photos. The media immediately picked up the story: they wanted details from her neighbours, her friends. They wanted to know what it was like to have someone else's face; what it was like for her family and the family of the donor. They discussed whether she would be able to kiss, to have a new relationship, to return to her old existence. Life was never the same again for Isabelle. She remained dependent on her doctors and did not return to full time work. She constantly watched her skin for signs of tissue rejection. She lived with a face that she described as half her own and half somebody else's. When Isabelle died of cancer in 2016, her doctors denied it was in any way connected to the cocktail of immunosuppressant drugs she had been taking - though those drugs are known to increase the risk of cancer. I have written in detail about Dinoire elsewhere. Her case is important - not just because of her own experiences as a female patient undertaking a cutting-edge technique, but also because it draws attention to the limits and obligations of what has been called 'Frankenstein science'. Where do we draw the line in medical experimentation? What can and can't be transplanted? Who decides?

I have not included images of Isabelle Dinoire in this blog post, since some readers might find them upsetting. But they are widely available online. So, too, are images of her surgeons, Bernard Devauchelle and Jean-Michel Dubernard, who also performed the first hand transplant. The hand transplant was not ultimately a success, because Clint Hallam, the recipient, could not bear living with it or dealing with the possibility of tissue rejection that occurred. For transplants to hold, massive amounts of immunosuppressants must be taken. Doctors are experimenting with alternative methods, but to date these have been unsuccessful. 

The history of face transplants is a history of experimentation, of trying to master the complexities of the different tissues making up the face. People with transplanted faces do not gain full facial mobility, so in addition to belonging to the realms of both the living and the dead, they are both healed and not healed. Isabelle Dinoire said that she felt like a 'monster' before her operation, when her wounds were visible and like a 'circus freak' afterwards, when everybody knew that she was the first face transplant recipient. Other people's responses to disfigurement and transplantation are hugely important. Face transplant surgery can be traced back to World War I and to the development of plastic and reconstructive techniques as a consequence of soldiers being wounded in ways and numbers never before seen. 

Another History Girl, Louisa Young, has written beautifully on questions of facial reconstructive surgery and social rehabilitation in My dear I wanted to tell you and the follow-up novels, The Heroes' Welcome and Devotion. I first met Louisa in 2006, when we were both contributing to the Wellcome Trust's first public exhibition, which was on hearts. Louisa had written her glorious Book of the Heart and I was working on a history monograph, Matters of the Heart: History, Medicine, Emotion. Eleven years later, by a wonderful serendipity, I find myself working on the history of face transplants soon after the publication of My Dear, I have something to tell you.  

Maybe that isn't such a coincidence as it might appear. After all, hearts and faces have a lot in common. I became interested in the history of transplants because of what they tell us about our bodies - and how we feel about them. Heart transplant patients often claim they have received more than a stranger's heart; stories abound of people's personality or even their cravings and abilities changing as a result. Transplants are gifts, from one person to another (at least in the UK where donors are not paid). They provoke a range of emotional responses: fear of having a new organ, disgust that organ is assimilated into their own bodies, gratitude to the donor, guilt that s/he has died while the recipient lives on, and so on. Isabelle expressed both revulsion that her tongue touched the dead lips of her donor as well as gratitude for her new face. There is an added poignancy to the fact that Dinoire's donor was a young woman who committed suicide. In life as in death, the two were linked together forever.